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Senior Manager

AstraZeneca

Canada · On-site Full-time Senior 1mo ago

About the role

About

Join Alexion in a Senior Manager role focusing on clinical pharmacology and quantitative analysis. This position emphasizes the development of innovative modeling strategies while working in a collaborative office environment.

In this role, you will lead modeling and simulation efforts for drug candidates throughout the clinical development pipeline. The Senior Manager will integrate quantitative approaches to enhance decision-making processes and collaborate with various departments, including Biostatistics and Translational Medicine. This role requires strong expertise in pharmacometrics and the ability to manage simultaneous projects while preparing documentation for regulatory submissions.

Shape the future of rare disease medicine at Alexion with your expertise and passion for analytics.

Responsibilities

  • Develop integrated M&S plans for drug development
  • Contribute to critical milestone decisions using quantitative data
  • Collaborate with external service providers on QSP models
  • Conduct population PK analyses and simulations
  • Prepare regulatory submission documentation efficiently

Requirements

  • PhD in relevant quantitative discipline
  • Minimum 2 years in clinical pharmacology or similar
  • Hands-on experience with R, SAS, and NONMEM
  • Background in MATLAB or QSP tools
  • Proven publication record in pharmacometrics

Skills

MATLABNONMEMQSPRSAS

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