Consultant

About TraceLine Solutions

TraceLine Solutions GmbH is a Zurich-based life sciences data company specialized in biomedical data science, semantic architecture, and regulatory bioinformatics. We specialise in turning fragmented research data into structured, machine-readable assets through ontology-driven design, data lineage, and standards-aligned automation.

Our clients are biotech and life sciences organisations navigating the complexity of clinical, genomic, and real-world data from trial design and data standards governance to cross-source harmonisation and precision medicine applications. We work at the technical frontier of the field, where computable science meets regulatory rigour.

TraceLine Solutions is early-stage and founder-led. We are building a small, senior team where each person owns their domain and contributes directly to the company's scientific and commercial trajectory.

The Role

We are looking for a consultant whose primary expertise sits in semantic web technologies and knowledge representation, applied to biomedical and clinical data. You will work alongside our clinical data standards specialist to design and deliver data architectures that are both computable and regulatory-ready, serving clients across clinical informatics, genomics, and precision medicine.

This is an 80–100% role for a senior specialist who wants to do substantive, technically demanding work in a lean, high-autonomy environment.

What You Will Do

• Design ontology-based information architectures for clinical, genomic, and real-world data, including knowledge graph modelling, entity resolution, and cross-domain concept alignment
• Build and maintain semantic layers using RDF, OWL, SPARQL, and linked data principles to support federated querying across heterogeneous biomedical sources
• Map and harmonise data across clinical and genomic standards: FHIR, HL7, SNOMED CT, ICD, MedDRA, HPO, HGVS, with a focus on computable interoperability
• Translate clinical trial eligibility criteria and protocol specifications into ontology-driven, database-queryable formats
• Collaborate with our clinical data standards consultants to ensure semantic architectures align with CDISC requirements (SDTM, ADaM, CDASH) and applicable regulatory frameworks
• Support data governance documentation, data lineage frameworks, and variant annotation pipeline design
• Contribute to scientific validation, data partnership development, grant applications, and investor materials as relevant

Your Profile

• Demonstrated expertise in semantic web technologies: OWL, RDF/RDFS, SPARQL, ontology engineering, and knowledge graph construction
• Solid working knowledge of biomedical ontologies and terminologies: SNOMED CT, HPO, HGVS, MedDRA, ICD, FHIR/HL7
• Familiarity with clinical data standards sufficient to operate in regulated life sciences environments (CDISC experience is an asset)
• Background in bioinformatics, computational biology, biomedical informatics, or a closely related field
• Track record of delivering in client-facing or project-based contexts
• Based in Switzerland or holding the right to work in Switzerland
• Fluency in English; French or German is an advantage

What We Offer

• A technically demanding, high-autonomy, rewarding environment at the frontier of biomedical data science
• Correct base salary commensurate with seniority, plus equity compensation
• Flexible working arrangements: remote within Switzerland, with presence in Zurich as required
• A founding-team environment where your work shapes both the product and the company

How to Apply

Submit your CV and a brief cover note outlining your relevant experience via the application link. We review applications on a rolling basis and will contact shortlisted candidates directly.