Founding Architect, Life Science AI

Your Impact at LILA

Lila is embarking on a transformative mission to redefine the future of medicine by combining automated large-scale data generation with scientific superintelligence. At Lila, we don't just use AI to analyze biology; we are building the loop where AI and automation co-evolve to solve the hardest problems in medicine. To this end, we are forming a new function, Life Science AI (LSAI), with the goal of researching automated reasoning on biological data by combining state-of-the-art machine learning with breakthrough biology. As a member of the LSAI leadership team, you will be a founding architect of this vision. You will play a critical role in shaping the culture, technical strategy, and therapeutic impact of AI at Lila. This is a high-impact leadership role reporting directly to the SVP of Life Science AI. Depending on the candidate’s depth of expertise, this role may focus on a single domain or span multiple pillars to drive platform-wide AI strategies.

What You'll Be Building

Team Leadership & Scientific Strategy

• Recruit, mentor, and lead a high-performing team of ML researchers and computational biologists.
• Foster a culture of "bilingual" excellence that thrives at the intersection of AI and biology.

Cross-Functional Synergy

• Act as the primary bridge to our Life Science Experimental Research team.
• You will ensure computational designs are optimized for "wet-lab" validation and architect the active learning feedback loops that allow experimental data to continuously improve our generative models.

Product Integration

• Partner with Life Science Product Management to align technical innovations with Lila’s commercial goals, ensuring our AI capabilities translate directly into therapeutic priorities.

Foundational Culture

• As a founding member of LSAI, you will establish the standards for engineering excellence, reproducible research, and collaborative innovation across the organization.

What You’ll Need to Succeed

Areas of Impact

Successful candidates will demonstrate deep expertise in one or more of the following areas. The final scope of the role will be tailored to the leader’s unique background:

• Protein Design: De novo protein scaffolds, binders, therapeutic antibodies, and enzyme engineering.
• Nucleic Acid Engineering: DNA/RNA vaccines, regulatory elements (UTRs, promoters), and viral vector optimization.
• Cell Biology: Foundation models for -omics (e.g., scRNAseq), perturbation data, and spatial profiling to drive target identification and mechanism-of-action studies.

Education

• PhD with a focus on computation, specifically in Computational Biology, Computer Science, or AI-driven drug discovery.

Technical Track Record

• Publications in top AI/ML & Scientific conferences (NeurIPS, ICML, ICLR, ACL & Nature, Science, Cell Press Matter, IOP).

Leadership

• Demonstrated experience building and leading multidisciplinary teams and managing complex research portfolios in a fast-paced environment.

Communication

• Exceptional skills in translating high-dimensional ML concepts for biological scientists and presenting strategic visions to executive stakeholders.

Bonus Points For

• Location: This role is based in San Francisco, CA or Boston, MA, with a strong preference for candidates located in or willing to relocate to San Francisco.

Compensation

We offer competitive compensation including bonus potential and generous early equity. The final offer will reflect your unique background, expertise, and impact. Expected Base Salary Range $360,000 — $570,000 USD

About LILA

Lila Sciences is building Scientific Superintelligence™ to solve humankind's greatest challenges. We believe science is the most inspiring frontier for AI. Rather than hard-coding expert knowledge into tools, LILA builds systems that can learn for themselves. LILA combines advanced AI models with proprietary AI Science Factory™ instruments into an operating system for science that executes the entire scientific method autonomously, accelerating discovery at unprecedented speed, scale, and impact across medicine, materials, and energy. Learn more at www.lila.ai.

Guided by our core values of truth, trust, curiosity, grit, and velocity, we move with startup speed while tackling problems of historic importance. If this sounds like an environment you'd love to work in, even if you don't meet every qualification listed above, we encourage you to apply.

We’re All In

Lila Sciences is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. Information you provide during your application process will be handled in accordance with our Candidate Privacy Policy .

A Note to Agencies

Lila Sciences does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lila Sciences or its employees is strictly prohibited unless contacted directly by Lila Science’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lila Sciences, and Lila Sciences will not owe any referral or other fees with respect thereto.